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1

Molecular Biology of Alzheimer’s Dementia and Its Clinical Relevance to Early Diagnosis and New Therapeutic Strategies

Wiltfang, Jens, Esselmann, Hermann, Maler, Juan Manuel, Bleich, Stefan, Hüther, Gerald, Kornhuber, Johannes

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 225 KB

english, 2001

2

Genetic Consequences of the Transatlantic Slave Trade in the Americas

Micheletti, Steven J., Bryc, Kasia, Ancona Esselmann, Samantha G., Freyman, William A., Moreno, Meghan E., Poznik, G. David, Shastri, Anjali J., Beleza, Sandra, Mountain, Joanna L., Agee, M., Aslibeky

Journal:

The American Journal of Human Genetics

Année:

2020

Fichier:

PDF, 1.79 MB

2020

3

Urea-based two-dimensional electrophoresis of beta-amyloid peptides in human plasma: Evidence for novel Aβ species

Juan Manuel Maler, Hans-Wolfgang Klafki, Sabine Paul, Philipp Spitzer, Teja Wolfgang Groemer, Andreas Wolfram Henkel, Hermann Esselmann, Piotr Lewczuk, Johannes Kornhuber, Jens Wiltfang

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 249 KB

english, 2007

4

CSF amyloid-β 1-38 and 1-42 in FTD and AD: Biomarker performance critically depends on the detergent accessible fraction

Mirko Bibl, Piotr Lewczuk, Hermann Esselmann, Brit Mollenhauer, Hans-Wolfgang Klafki, Volker Welge, Stefanie Wolf, Claudia Trenkwalder, Markus Otto, Johannes Kornhuber, Jens Wiltfang

Journal:

PROTEOMICS - Clinical Applications

Année:

2008

Langue:

english

Fichier:

PDF, 312 KB

english, 2008

5

The amyloid-β (Aβ) peptide pattern in cerebrospinal fluid in Alzheimer's disease: evidence of a novel carboxyterminally elongated Aβ peptide

Piotr Lewczuk, Hermann Esselmann, Markus Meyer, Volker Wollscheid, Manuela Neumann, Markus Otto, Juan Manuel Maler, Eckart Rüther, Johannes Kornhuber, Jens Wiltfang

Journal:

Rapid Communications in Mass Spectrometry

Année:

2003

Langue:

english

Fichier:

PDF, 135 KB

english, 2003

6

The classification of compact hyperbolic Coxeterd-polytopes withd+2 facets

Frank Esselmann

Journal:

Commentarii Mathematici Helvetici

Année:

1996

Langue:

english

Fichier:

PDF, 556 KB

english, 1996

7

Combined CSF tau, p-tau181 and amyloid-β 38/40/42 for diagnosing Alzheimer’s disease

Volker Welge, Oliver Fiege, Piotr Lewczuk, Brit Mollenhauer, Hermann Esselmann, Hans-Wolfgang Klafki, Stefanie Wolf, Claudia Trenkwalder, Markus Otto, Johannes Kornhuber, Jens Wiltfang, Mirko Bibl

Journal:

Journal of Neural Transmission

Année:

2009

Langue:

english

Fichier:

PDF, 258 KB

english, 2009

8

Blood-based neurochemical diagnosis of vascular dementia: a pilot study

Mirko Bibl, Hermann Esselmann, Brit Mollenhauer, Godehard Weniger, Volker Welge, Michael Liess, Piotr Lewczuk, Markus Otto, Jörg B Schulz, Claudia Trenkwalder, Johannes Kornhuber, Jens Wiltfang

Journal:

Journal of Neurochemistry

Année:

2007

Langue:

english

Fichier:

PDF, 345 KB

english, 2007

9

Tau protein phosphorylated at threonine 181 in CSF as a neurochemical biomarker in Alzheimer’s disease

Piotr Lewczuk, Hermann Esselmann, Mirko Bibl, Georg Beck, Juan Manuel Maler, Markus Otto, Johannes Kornhuber, Jens Wiltfang

Journal:

Journal of Molecular Neuroscience

Année:

2004

Langue:

english

Fichier:

PDF, 100 KB

english, 2004

10

Memantine inhibits ethanol-induced NMDA receptor up-regulation in rat hippocampal neurons

Juan Manuel Maler, Hermann Esselmann, Jens Wiltfang, Nikolaus Kunz, Piotr Lewczuk, Udo Reulbach, Stefan Bleich, Eckart Rüther, Johannes Kornhuber

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 210 KB

english, 2005

11

Distinct fractional Aβ release patterns in human mononuclear phagocytes

Juan Manuel Maler, Philipp Spitzer, Hans-Wolfgang Klafki, Hermann Esselmann, Piotr Lewczuk, Johannes Kornhuber, Martin Herrmann, Jens Wiltfang

Journal:

Journal of Neuroimmunology

Année:

2009

Langue:

english

Fichier:

PDF, 286 KB

english, 2009

12

Adherence-dependent shifts in the patterns of β-amyloid peptides secreted by human mononuclear phagocytes

Juan Manuel Maler, Philipp Spitzer, Hans-Wolfgang Klafki, Hermann Esselmann, Mirko Bibl, Piotr Lewczuk, Johannes Kornhuber, Martin Herrmann, Jens Wiltfang

Journal:

Brain, Behavior, and Immunity

Année:

2008

Langue:

english

Fichier:

PDF, 441 KB

english, 2008

13

Multiplexed quantification of dementia biomarkers in the CSF of patients with early dementias and MCI: A multicenter study

Piotr Lewczuk, Johannes Kornhuber, Hugo Vanderstichele, Eugeen Vanmechelen, Hermann Esselmann, Mirko Bibl, Stefanie Wolf, Markus Otto, Udo Reulbach, Heike Kölsch, Frank Jessen, Johannes Schröder, Pete

Journal:

Neurobiology of Aging

Année:

2008

Langue:

english

Fichier:

PDF, 497 KB

english, 2008

14

Neurochemical diagnosis of Alzheimer’s dementia by CSF Aβ42, Aβ42/Aβ40 ratio and total tau

Piotr Lewczuk, Hermann Esselmann, Markus Otto, Juan Manuel Maler, Andreas Wolfram Henkel, Maria Kerstin Henkel, Oliver Eikenberg, Christof Antz, Wolf-Rainer Krause, Udo Reulbach, Johannes Kornhuber, J

Journal:

Neurobiology of Aging

Année:

2004

Langue:

english

Fichier:

PDF, 188 KB

english, 2004

15

S1-02-03 Neuroproteomic profiling of amyloid beta peptides in human CSF with SELDI-TOF MS

Jens Wiltfang, Hermann Esselmann, Mirko Bibl, Johannes Kornhuber, Piotr Lewczuk

Journal:

Neurobiology of Aging

Année:

2004

Langue:

english

Fichier:

PDF, 161 KB

english, 2004

16

O4-04-03 Lithium decreases secretion of Abeta 1–42 and C-truncated species Abeta 1-37/38/39/40 in chicken telencephalic cultures but specifically increases intracellular Abeta 1–38

Hermann Esselmann, Nikolaus Kunz, Juan M. Maler, Piotr Lewczuk, Markus Otto, Eckart Ruether, Johannes Kornhuber, Jens Wiltfang

Journal:

Neurobiology of Aging

Année:

2004

Langue:

english

Fichier:

PDF, 320 KB

english, 2004

17

P2-052: Chicken primary neuronal cells as a powerful model for studying tau phosphorylation, APP processing and Aβ generation

Juan Manuel Maler, Hans W. Klafki, Hermann Esselmann, Nikolaus Kunz, Sabine Paul, Johannes Kornhuber, Jens Wiltfang

Journal:

Alzheimer's & Dementia

Année:

2006

Langue:

english

Fichier:

PDF, 56 KB

english, 2006

18

P2-157: Expression of CSF amyloid beta peptide patterns Alzheimer’s disease, dementia with Lewy bodies and Parkinson’s disease dementia

Mirko Bibl, Brit Mollenhauer, Hermann Esselmann, Piotr Lewczuk, Hans-Wolfgang Klafki, Katrin Sparbier, Alexandr Smirnov, Lukas Cepek, Claudia Trenkwalder, Eckart Ruther, Johannes Kornhuber, Markus Ott

Journal:

Alzheimer's & Dementia

Année:

2006

Langue:

english

Fichier:

PDF, 69 KB

english, 2006

19

P2-146: Multiplexed quantification of dementia biomarkers in the cerebrospinal fluid: A multicenter study

Piotr Lewczuk, Hugo Vanderstichele, Eugeen Vanmechelen, Hermann Esselmann, Mirko Bibl, Juan Manuel Maler, Johannes Kornhuber, Jens Wiltfang

Journal:

Alzheimer's & Dementia

Année:

2006

Langue:

english

Fichier:

PDF, 57 KB

english, 2006

20

O2-03-04: Aph1B gamma-secretase generates long Abeta peptides and genetic ablation improves Alzheimer's disease phenotypes without affecting notch signaling in the mouse

Lutgarde Serneels, Jérôme Van Biervliet, Katleen Craessaerts, Tim Dejaegere, Katrien Horré, Tine Van Houtvin, Hermann Esselmann, Sabine Paul, Ben Sprangers, Raf Sciot, Lieve Moons, Mathias Jucker, Jen

Journal:

Alzheimer's & Dementia

Année:

2008

Langue:

english

Fichier:

PDF, 62 KB

english, 2008

21

Amyloid β peptides in cerebrospinal fluid as profiled with surface enhanced laser desorption/ionization time-of-flight mass spectrometry: evidence of novel biomarkers in Alzheimer's disease

Piotr Lewczuk, Hermann Esselmann, Teja Wolfgang Groemer, Mirko Bibl, Juan Manuel Maler, Petra Steinacker, Markus Otto, Johannes Kornhuber, Jens Wiltfang

Journal:

Biological Psychiatry

Année:

2004

Langue:

english

Fichier:

PDF, 218 KB

english, 2004

22

Polymeric Complements to the Alzheimer's Disease Biomarker β-Amyloid Isoforms Aβ1–40 and Aβ1–42 for Blood Serum Analysis under Denaturing Conditions

Urraca, Javier L., Aureliano, Carla S. A., Schillinger, Eric, Esselmann, Hermann, Wiltfang, Jens, Sellergren, Börje

Journal:

Journal of the American Chemical Society

Année:

2011

Langue:

english

Fichier:

PDF, 1.68 MB

english, 2011

23

-Secretase Heterogeneity in the Aph1 Subunit: Relevance for Alzheimer's Disease

Serneels, L., Van Biervliet, J., Craessaerts, K., Dejaegere, T., Horre, K., Van Houtvin, T., Esselmann, H., Paul, S., Schafer, M. K., Berezovska, O., Hyman, B. T., Sprangers, B., Sciot, R., Moons, L.,

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 861 KB

english, 2009

24

From Bones to Brain: 50 Years of Star Trek and Changes in the Stigmatization of Psychological Disorders

Basilowski, M., Schönfeld, B., Esser, S., Jatho, A., Kownatka, M., Signerski-Krieger, J., Esselmann, H., Grabemann, M., Mette, C., Strunz, L., Zimmermann, M., Lajcsak, E., Scherbaum, N., Wiltfang, J.,

Journal:

Current Psychology

Année:

2018

Langue:

english

Fichier:

PDF, 593 KB

english, 2018

25

% in Alzheimer's Disease, Dementia with Lewy Bodies and Parkinson's Disease Dementia

Bibl, Mirko, Esselmann, Hermann, Lewczuk, Piotr, Trenkwalder, Claudia, Otto, Markus, Kornhuber, Johannes, Wiltfang, Jens, Mollenhauer, Brit

Journal:

International Journal of Alzheimer's Disease

Année:

2010

Langue:

english

Fichier:

PDF, 1.30 MB

english, 2010

26

β-amyloid peptides in cerebrospinal fluid of patients with Creutzfeldt–Jakob disease

Jens Wiltfang, Hermann Esselmann, Alexander Smirnov, Mirko Bibl, Lukas Cepek, Petra Steinacker, Brit Mollenhauer, Katharina Buerger, Harald Hampel, Sabine Paul, Manuela Neumann, Manuel Maler, Inga Zer

Journal:

Annals of Neurology

Année:

2003

Langue:

english

Fichier:

PDF, 129 KB

english, 2003

27

Cerebrospinal fluid amyloid β peptide patterns in Alzheimer's disease patients and nondemented controls depend on sample pretreatment: Indication of carrier-mediated epitope masking of amyloid β peptides

Mirko Bibl, Hermann Esselmann, Markus Otto, Piotr Lewczuk, Lukas Cepek, Eckart Rüther, Johannes Kornhuber, Jens Wiltfang

Journal:

ELECTROPHORESIS

Année:

2004

Langue:

english

Fichier:

PDF, 108 KB

english, 2004

28

Electrophoretic separation of amyloid β peptides in plasma

Piotr Lewczuk, Hermann Esselmann, Mirko Bibl, Sabine Paul, Jana Svitek, Johannes Miertschischk, Robert Meyrer, Alexandr Smirnov, Juan Manuel Maler, Christian Klein, Markus Otto, Stefan Bleich, Wolfgan

Journal:

ELECTROPHORESIS

Année:

2004

Langue:

english

Fichier:

PDF, 163 KB

english, 2004

29

Stability of amyloid-β peptides in plasma and serum

Mirko Bibl, Volker Welge, Hermann Esselmann, Jens Wiltfang

Journal:

ELECTROPHORESIS

Année:

2012

Langue:

english

Fichier:

PDF, 164 KB

english, 2012

30

Recurrent systemic infections with Streptococcus pneumoniae do not aggravate the course of experimental neurodegenerative diseases

Sandra Ebert, Miriam Goos, Lena Rollwagen, Daniel Baake, Wolf-Dieter Zech, Hermann Esselmann, Jens Wiltfang, Brit Mollenhauer, Reinhard Schliebs, Joachim Gerber, Roland Nau

Journal:

Journal of Neuroscience Research

Année:

2010

Langue:

english

Fichier:

PDF, 680 KB

english, 2010

31

Über die maximale Dimension von Lorentz–Gittern mit coendlicher Spiegelungsgruppe

Frank Esselmann

Journal:

Journal of Number Theory

Année:

1996

Fichier:

PDF, 1.77 MB

1996

32

Highly conserved and disease-specific patterns of carboxyterminally truncated Aβ peptides 1–37/38/39 in addition to 1–40/42 in Alzheimer's disease and in patients with chronic neuroinflammation

J. Wiltfang, H. Esselmann, M. Bibl, A. Smirnov, M. Otto, S. Paul, B. Schmidt, H.-W. Klafki, M. Maler, T. Dyrks, M. Bienert, M. Beyermann, E. Rüther, J. Kornhuber

Journal:

Journal of Neurochemistry

Année:

2002

Langue:

english

Fichier:

PDF, 489 KB

english, 2002

33

Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated

Sandra I Vieira, Sandra Rebelo, Hermann Esselmann, Jens Wiltfang, James Lah, Rachel Lane, Scott A Small, Sam Gandy, Edgar F da Cruz e Silva, Odete AB da Cruz e Silva

Journal:

Molecular Neurodegeneration

Année:

2010

Langue:

english

Fichier:

PDF, 10.48 MB

english, 2010

34

Das System Schwefelsäure-Natriumsulfat-Wasser

O. Faust, P. Esselmann

Journal:

Zeitschrift für anorganische und allgemeine Chemie

Année:

1926

Langue:

german

Fichier:

PDF, 436 KB

german, 1926

35

Tacrolimus (FK 506) biotransformation in primary rat hepatocytes depends on extracellular matrix geometry

A. Bader, E. Knop, K. H. W. Böker, O. Crome, N. Frühauf, A. K. Gonschior, U. Christians, H. Esselmann, R. Pichlmayr, K. -F. Sewing

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Année:

1996

Langue:

english

Fichier:

PDF, 4.11 MB

english, 1996

36

Differential effects of visual-spatial attention on response latency and temporal-order judgment

Odmar Neumann, Ute Esselmann, Werner Klotz

Journal:

Psychological Research

Année:

1993

Langue:

english

Fichier:

PDF, 1.07 MB

english, 1993

37

Exposure to allergens of different cattle breeds and their relevance in occupational allergy

Astrid R. R. Heutelbeck, Carsten Junghans, Hermann Esselmann, Ernst Hallier, Thomas G. Schulz

Journal:

International Archives of Occupational and Environmental Health

Année:

2009

Langue:

english

Fichier:

PDF, 377 KB

english, 2009

38

CSF diagnosis of Alzheimer’s disease and dementia with Lewy bodies

M. Bibl, B. Mollenhauer, H. Esselmann, P. Lewczuk, C. Trenkwalder, P. Brechlin, E. Rüther, J. Kornhuber, M. Otto, J. Wiltfang

Journal:

Journal of Neural Transmission

Année:

2006

Langue:

english

Fichier:

PDF, 186 KB

english, 2006

39

Tauopathies and synucleinopathies: Do cerebrospinal fluid β-amyloid peptides reflect disease-specific pathogenesis?

B. Mollenhauer, M. Bibl, H. Esselmann, P. Steinacker, C. Trenkwalder, J. Wiltfang, M. Otto

Journal:

Journal of Neural Transmission

Année:

2007

Langue:

english

Fichier:

PDF, 359 KB

english, 2007

40

Reduced CSF carboxyterminally truncated Aβ peptides in frontotemporal lobe degenerations

M. Bibl, B. Mollenhauer, S. Wolf, H. Esselmann, P. Lewczuk, J. Kornhuber, J. Wiltfang

Journal:

Journal of Neural Transmission

Année:

2007

Langue:

english

Fichier:

PDF, 152 KB

english, 2007

41

Different CSF β-amyloid processing in Alzheimer’s and Creutzfeldt–Jakob disease

Brit Mollenhauer, Hermann Esselmann, Sigrun Roeber, Walter J. Schulz-Schaeffer, Claudia Trenkwalder, Mirko Bibl, Petra Steinacker, Hans A. Kretzschmar, Jens Wiltfang, Markus Otto

Journal:

Journal of Neural Transmission

Année:

2011

Langue:

english

Fichier:

PDF, 246 KB

english, 2011

42

Erratum to: Different CSF β-amyloid processing in Alzheimer’s and Creutzfeldt–Jakob disease

Brit Mollenhauer, Hermann Esselmann, Sigrun Roeber, Walter J. Schulz-Schaeffer, Claudia Trenkwalder, Mirko Bibl, Petra Steinacker, Hans A. Kretzschmar, Jens Wiltfang, Markus Otto

Journal:

Journal of Neural Transmission

Année:

2011

Langue:

english

Fichier:

PDF, 125 KB

english, 2011

43

Tyr687dependent APP endocytosis and abeta production

S. Rebelo, S. I. Vieira, O. A. B. da Cruz e Silva, H. Esselmann, J. Wiltfang, E. F. da Cruz e Silva

Journal:

Journal of Molecular Neuroscience

Année:

2007

Langue:

english

Fichier:

PDF, 1.51 MB

english, 2007

44

Amyloid beta peptide 1–40 enhances the action of Toll-like receptor-2 and -4 agonists but antagonizes Toll-like receptor-9-induced inflammation in primary mouse microglial cell cultures

Miriam Lotz, Sandra Ebert, Hermann Esselmann, Asparouh I. Iliev, Marco Prinz, Nicole Wiazewicz, Jens Wiltfang, Joachim Gerber, Roland Nau

Journal:

Journal of Neurochemistry

Année:

2005

Langue:

english

Fichier:

PDF, 576 KB

english, 2005

45

Presenilin clinical mutations can affect γ-secretase activity by different mechanisms

Mostafa Bentahir, Omar Nyabi, Jan Verhamme, Alexandra Tolia, Katrien Horré, Jens Wiltfang, Hermann Esselmann, Bart De Strooper

Journal:

Journal of Neurochemistry

Année:

2006

Langue:

english

Fichier:

PDF, 771 KB

english, 2006

46

Amyloid β peptide ratio 42/40 but not Aβ42 correlates with phospho-Tau in patients with low- and high-CSF Aβ40 load

Jens Wiltfang, Hermann Esselmann, Mirko Bibl, Michael Hüll, Harald Hampel, Holger Kessler, Lutz Frölich, Johannes Schröder, Oliver Peters, Frank Jessen, Christian Luckhaus, Robert Perneczky, Holger Ja

Journal:

Journal of Neurochemistry

Année:

2007

Langue:

english

Fichier:

PDF, 506 KB

english, 2007

47

Immune complexes of auto-antibodies against Aβ1-42 peptides patrol cerebrospinal fluid of non-Alzheimer's patients

Henkel, A W, Dittrich, P S, Groemer, T W, Lemke, E A, Klingauf, J, Klafki, H W, Lewczuk, P, Esselmann, H, Schwille, P, Kornhuber, J

Journal:

Molecular Psychiatry

Année:

2007

Langue:

english

Fichier:

PDF, 279 KB

english, 2007

48

Validation of amyloid-β peptides in CSF diagnosis of neurodegenerative dementias

Bibl, M, Mollenhauer, B, Lewczuk, P, Esselmann, H, Wolf, S, Trenkwalder, C, Otto, M, Stiens, G, Rüther, E, Kornhuber, J

Journal:

Molecular Psychiatry

Année:

2007

Langue:

english

Fichier:

PDF, 164 KB

english, 2007

49

Plasma Amyloid-BetaPeptides in Acute Cerebral Ischemia: A Pilot Study

Mirko Bibl, Volker Welge, Holger Schmidt, Hermann Esselmann, Brit Mollenhauer, Piotr Lewczuk, Markus Otto, Johannes Kornhuber, Jens Wiltfang

Journal:

Journal of Clinical Laboratory Analysis

Année:

2012

Langue:

english

Fichier:

PDF, 569 KB

english, 2012

50

Characterization of cerebrospinal fluid aminoterminally truncated and oxidized amyloid-β peptides

Mirko Bibl, Marion Gallus, Volker Welge, Sabine Lehmann, Katrin Sparbier, Hermann Esselmann, Jens Wiltfang

Journal:

PROTEOMICS - Clinical Applications

Année:

2012

Langue:

english

Fichier:

PDF, 660 KB

english, 2012